Lung Cancer: Targets and Therapy
نویسندگان
چکیده
s excluded as irrelevant (n = 1320) Full text paper obtained for further review (n = 164) 99 studies further excluded: • • • • • • • No astragalus involved in TCM treatment (n = 54) Not all subjects received astragalus-based TCM (n = 8) No platinum included in the chemotherapy or chemotherapy combined with radiotherapy (n = 10) No usable endpoints were included (n = 16) Not a controlled trial (n = 3) Duplicated study (n = 4) Not all subjects suffered from NSCLC (n = 4) Studies included in final meta-analysis (n = 65) Figure 1 Flow diagram of included studies. Lu ng C an ce r: T ar ge ts a nd T he ra py d ow nl oa de d fr om h ttp s: //w w w .d ov ep re ss .c om / b y 54 .7 0. 40 .1 1 on 2 1Ja n20 18 F or p er so na l u se o nl y. Powered by TCPDF (www.tcpdf.org)
منابع مشابه
Bioinformatics identification of miRNA-mRNA regulatory network contributing to lung cancer invasion
Background: Over the past 15 years, significant insights have been gained into the roles of miRNAs in cancer. In various cancers, miRNAs can act as oncogenes, tumor suppressors, or control the metastasis process by modulating the expression of numerous target genes. This study is aimed at determining molecular network of miRNA-mRNA regulating lung cancer invasion, by bioinformatics approaches. ...
متن کاملBioinformatics Identification of miRNA-mRNA Regulatory Network Contributing Primary Lung Cancer
Introduction: In clinical practice, distinguishing invasive lung tumors from primary tumors remains a challenge. With recent advances in understanding biological alterations of tumorigenesis and molecular analytic technologies, using these molecular alterations can be sensitive and tumor-specific as biomarker for the stratification of patients. In this study, the molecular network of miRNA-mRNA...
متن کاملRespiratory motion effect on tumor and normal tissue doses in patients with lung cancer, treated with Intensity Modulation Radiation Therapy and Three Dimensional Conformal Radiation Therapy.
Introduction: The aim of this study is to investigate the effect of respiratory motion during radiation therapy in patient with lung cancer and comparison of dosimetric parameters between Intensity modulation radiation therapy and three-dimensional conformal radiotherapy in lung cancer. Materials and Methods: Two CT scan was performred for each pati...
متن کاملMolecular targets of pomegranate (Punica granatum) in preventing cancer metastasis
Metastasis is the primary cause of mortality and morbidity among cancer patients and accounts for about 90% of cancer deaths. The most common types of treatment for cancer metastasis are chemotherapy and radiotherapy. However, such therapy has many serious side effects that could diminish the quality of life in patients. There is increased appreciation by the scientific community that natural c...
متن کاملTwo Lung Cancer Development-Related Genes, Forkhead Box M1 (FOXM1) and Apolipoprotein E (APOE), are overexpressed in Bronchial of Patients after Long-Term Exposure to Sulfur Mustard
Sulfur mustard (SM) is a strong alkylating and mutagenic compound that targets humanairway system. We considered the expression of Forkhead box M1 (FOXM1) and apolipoproteinE (APOE) genes, which are responsible for cell proliferation, differentiation, tumorigenesis,and increased risk of lung cancer, in the lung bronchial tissue of patients exposed to SM.After performing pulmonary functional tes...
متن کاملATM induces radioresistance of non-small cell lung cancer A549 cells by downregulation of MDMX
Background: Tumor radioresistance leads to a reduction in the efficiency of radiation therapy. It is very important to explore the cellular mechanisms leading to radioresistance and to find potential therapeutic targets, which might improve the efficacy of radiation therapy. This study was to investigate the role of ataxia-telangiectasia mutated (ATM) and murine double minute X (MDMX) in radior...
متن کامل